What we do.
"We study cancer within the context of a person's life."
- Svasti Haricharan
DNA damage repair and the receptor landscape of the cell membrane
We are currently identifying how growth factor receptors in breast cancer cells are displayed, regulated, and activated in DNA damage repair deficient cells.
DNA repair proteins liaise between the cellular environment and the cell cycle. We are currently studying the molecular pathways underlying this messenger system.
DNA damage repair and the cell cycle
Racial disparities in breast cancer outcome
Black women are 40% more likely to die of their breast cancer diagnosis than white women. We study how social determinants of health influence molecular biology in cancer cells to result in this outcome disparity.
DNA damage repair defects cause a plethora of human disease, including cancer. We study race/ethnicity-based differences, organ specificity, timeline dependence, and cellular localization of DNA repair proteins and their effects on the development and progression of cancer.